Copy number aberrations at chromosomal region 8q24 occur frequently in lymphomas and typically include the MYC gene.
The detection is based on a custom MLPA technique, using multiple probes in the region under investigation.
This test may also be applied in combination with:
- Karyotyping of bone marrow cells, combined with molecular detection of multiple chromosomal rearrangements
- Multicolor karyotype (M-FISH)